Open Targets How we improved our experimental data curation during the COVID-19 lockdown [9 minute read] Learn how we leveraged the wide range of expertise amongst our lab-based experimental research colleagues to make valuable contributions to our target validation projects.
Guest Speakers Open Targets hosts Kiran Musunuru: insights into the genetic basis of coronary heart disease [7 minute read] Open Targets recently hosted Prof. Kiran Musunuru, who discussed his work into the genetic basis of coronary heart disease.
experimental science Getting a finer view on genes leading to Alzheimer’s disease risk [4 minute read] In a paper recently published in Nature Genetics, Schwartzentruber and his colleagues found 37 regions associated with Alzheimer’s disease, including 4 regions which hadn’t previously been identified.
Open Targets How Open Targets is investigating 100 chromatin-related disorders | Rare Disease Day 2021 [5 minute read] Sebastian Gerety is a Senior Staff Scientist at the Wellcome Sanger Institute who oversees the the 100 chromatin-related disorders project. In honour of Rare Disease Day 2021, he told us about what they have been working on.
experimental science Q&A with Eddie Cano-Gámez, winner of the 2020 Charles J. Epstein Trainee Award What does a bald soprano have to do with genetics? If you’re Eddie Cano-Gámez, Eugene Ionesco’s absurdist play, The Bald Soprano (La Cantatrice Chauve), teaches you everything you need to know
experimental science In-GenIE-ous experiments to find causal variants from GWAS [5 minute read] We developed a new method that can be used to screen up to a few dozen SNPs for a causal effect on gene transcription. We call it GenIE — Genome engineering-based Interrogation of Enhancers, and it was recently published in Nucleic Acids Research.
Q&A Special Q&A with Gosia Trynka, Open Targets Experimental Science director We're delighted to have caught up with Gosia Trynka, our new Experimental Science director, for a very special Q&A on Open Targets science and more.
